Rabies prevention guidance
Practical advice for avoiding rabies and getting prompt care after exposure
Learn how to prevent animal bites, when to use pre-exposure vaccination, and why immediate wound care plus PEP can save lives.
Rabies Prevention, First Aid & PEP
Complete guide to preventing rabies and what to do after exposure. CDC-aligned protocols for immediate action.
- Rabies is preventable—vaccinating pets and avoiding wildlife are key.
- After a bite or scratch, wash and flush the wound with soap and running water for about 15 minutes when possible, then seek prompt medical or public-health guidance.
- PEP is highly effective when started before symptoms.
- Community dog vaccination (≥70% coverage) breaks transmission.
Immediate first aid
- 1.Wash and flush the wound with soap and running water for about 15 minutes when possible; apply povidone-iodine if available.
- 2.A clinician should decide whether and when wound closure is appropriate, including how RIG applies if it is indicated.
- 3.A healthcare professional should assess whether you need a tetanus vaccine based on the wound and your vaccination history. Antibiotics are not recommended to prevent tetanus; a clinician may prescribe them for other wound infections. See CDC tetanus wound-care guidance.
World Health Organization
CDC protocol when PEP is indicated and there is no prior vaccination
HRIG: 20 IU/kg once, preferably Day 0
CDC guidance describes administration into and around wounds, with any remainder given IM away from the vaccine site, and limits HRIG timing to the first 7 days after the initial vaccine dose. A clinician calculates and administers it.
CDC-described intramuscular vaccine regimen
The published schedule uses Days 0, 3, 7, and 14; clinicians may adapt the regimen for people with immune disorders.
CDC
CDC protocol when PEP is indicated after prior vaccination
HRIG is not included in the published protocol
Published vaccine schedule: Days 0 and 3
A clinician should confirm the prior vaccination history and regimen.
CDC
Clinician notes
Pregnancy/children are not contraindications to PEP.
Avoid gluteal injections.
Separate HRIG and vaccine sites.
CDC
WHO intradermal (ID) option (where used)
Resource-efficient schedule: 0.1 mL ID at 2 sites on Days 0, 3, 7 (Category II/III exposures). A clinician or public-health authority determines whether RIG is indicated and how its timing applies.
World Health Organization
Can PEP wait for observation/testing?
Seek prompt professional assessment after a possible exposure, including from a vaccinated pet. Public health may use supervised observation of an eligible dog, cat, or ferret or laboratory testing to guide PEP. Do not wait for results before seeking advice or change PEP on your own. In areas where dog rabies is common, observation must not delay indicated PEP.
CDC
Pre-Exposure Prophylaxis (PrEP) — travelers & high-risk jobs
2 doses on Days 0 & 7.
Then either a one-time titer between year 1–3 or a one-time booster between 3 weeks and 3 years after dose 1, depending on your risk category.
CDC
Pets & community prevention
- Vaccinate dogs/cats starting at ~12 weeks, then boosters per product/local law.
- Sustained ≥70% dog vaccination coverage is the key threshold for breaking transmission in communities.
- Spay/neuter programs reduce roaming and aggression, decreasing bite incidents.
- Animal control programs should include vaccination clinics and public education.
- Community education increases responsible pet ownership and timely veterinary care.
WHO Apps
Travel-Specific Rabies Prevention
Pre-Travel Preparation
- Research rabies risk at your destination using CDC travel health notices.
- Consider pre-exposure prophylaxis if traveling to high-risk areas for extended periods.
- Consult a travel medicine specialist 4-6 weeks before departure.
- Ensure routine vaccinations are up-to-date before travel.
- Purchase travel insurance that covers medical evacuation and rabies treatment.
During Travel Precautions
- Avoid contact with all mammals, including pets and wildlife, in rabies-endemic areas.
- Do not feed or handle stray animals, no matter how friendly they appear.
- Supervise children closely—they are more likely to approach animals and less likely to report bites.
- Avoid caves where bats may roost, especially in Southeast Asia and Latin America.
- Use bed nets in basic accommodations to prevent bat bites while sleeping.
High-Risk Destinations
Over 95% of human rabies deaths occur in Asia and Africa. Highest risk countries include:
- India (accounts for ~36% of global rabies deaths)
- Pakistan and Bangladesh
- Indonesia and other Southeast Asian countries
- Most African countries, particularly in rural areas
- Some parts of Latin America and the Caribbean
CDC Travel Health
Occupational Rabies Risks & Prevention
High-Risk Professions
- Veterinarians, animal technicians, and wildlife biologists
- Animal control officers and shelter workers
- Laboratory workers handling rabies virus or specimens
- Spelunkers (cave explorers) and bat researchers
- Forest rangers, wildlife officers, and trappers
- Postal workers and delivery personnel in rural areas
Occupational Prevention Strategies
- Pre-exposure vaccination is recommended for all high-risk professions.
- Use appropriate personal protective equipment (PPE) when handling animals.
- Implement engineering controls like animal restraint devices and barriers.
- Report all animal bites or exposures immediately to supervisors.
- Maintain vaccination records and ensure timely booster doses.
- Participate in regular rabies prevention training and drills.
See our personal & family safety practices guide for at-home and outdoor precautions, and our emergency response steps for what to do if an exposure happens despite precautions.
Employer Responsibilities
- Provide pre-exposure vaccination at no cost to employees.
- Develop and implement exposure control plans.
- Ensure access to post-exposure prophylaxis through occupational health.
- Maintain supplies of PPE and proper waste disposal systems.
- Encourage reporting without fear of reprisal.
OSHA/NIOSH Guidelines
What to do after an exposure
Clean the wound
Wash and flush with soap and running water for about 15 minutes when possible, then seek prompt medical or public-health guidance.
Contact public health
A clinician or public-health authority considers the animal, contact, local surveillance, and whether observation or testing is appropriate before advising about PEP.
Follow the professional care plan
If PEP is indicated, the CDC schedule differs for previously vaccinated people, people who are not vaccinated, and people with immune disorders.
FAQs
Need immediate help?
After a possible human exposure, contact a healthcare professional or local public-health authority for guidance on where to seek assessment.
Rabies Laws by State
Review vaccination rules, reporting requirements, and animal control regulations in your state.
Compare requirements in Texas, Florida, and California, then continue with our prevention blog, emergency guide, and exposure checklist.
References
- World Health Organization (WHO) — Rabies Fact Sheet: who.int/news-room/fact-sheets/detail/rabies
- Centers for Disease Control and Prevention (CDC) — Rabies Medical Care: cdc.gov/rabies/
- WHO position on dog vaccination coverage: who.int/activities/eliminating-dog-mediated-human-rabies
This page summarizes CDC/WHO guidance. Always follow your local health department's advice.
Last updated: September 5, 2026 | Sources: CDC, WHO, santacruzhealth.org
Common Rabies Myths & Facts
Myth: You can get rabies from petting a rabid animal
Fact: Rabies is transmitted through saliva entering the body, usually via a bite. Simply touching or petting an animal, even if rabid, does not transmit the virus unless there is an open wound or mucous membrane exposure to saliva.
Myth: Only dogs transmit rabies to humans
Fact: While dogs are the main source globally (up to 99% of transmissions), rabies can be transmitted by any mammal including bats, raccoons, skunks, foxes, and cats. In the Americas, bats are the leading cause of human rabies deaths.
Myth: You can tell if an animal has rabies by looking at it
Fact: You cannot determine if an animal has rabies by appearance alone. Some animals may act aggressively or unusually friendly, while others may show no visible signs. Laboratory testing is required for diagnosis.
Fact: Wound washing saves lives
WHO recommends extensive wound washing with soap and water for at least 15 minutes soon after a possible exposure. Wound washing is an important part of post-exposure care, but it does not replace prompt assessment by a healthcare professional or public-health authority.
Fact: Time passed is not a reason to avoid PEP assessment
Seek prompt medical or public-health assessment after a possible exposure. If PEP is indicated, it should be given before symptoms begin. There is no automatic cut-off simply because time has passed, so still seek professional guidance.
Global Rabies Elimination Efforts
The Zero by 30 Initiative
The World Health Organization (WHO), World Organisation for Animal Health (WOAH), Food and Agriculture Organization (FAO), and Global Alliance for Rabies Control (GARC) have united under the "United Against Rabies" framework to achieve zero human deaths from dog-mediated rabies by 2030.
Key Strategies
- Mass dog vaccination campaigns targeting ≥70% coverage in at-risk areas
- Improved access to affordable, quality-assured PEP and HRIG
- Enhanced surveillance and reporting systems
- Increased community awareness and education
- Dog population management through humane methods
- Research into new tools and strategies
Progress to Date
- Several countries in Latin America and the Caribbean have eliminated dog-mediated rabies
- Southeast Asian countries are making significant progress through vaccination campaigns
- African nations are expanding vaccination coverage with international support
- Human rabies deaths have decreased globally, but approximately 59,000 people still die annually
How You Can Help
- Ensure your pets are vaccinated against rabies
- Support organizations working on rabies elimination
- Report suspicious animal behavior to local authorities
- Educate others about rabies prevention and the importance of pet vaccination
- If traveling, consider donating to rabies prevention efforts in high-risk areas
WHO/WOAH/FAO/GARC